Fenever Pet Oral Suspension

Description / Action: 

Fenever Pet Oral Suspension (100 mg) contains fenbendazole which is a broad-spectrum benzimidazole anthelmintic used against gastrointestinal parasites including Giardia, roundworms, hookworms, whipworms, the tapeworms against genus Taenia, Aelurostrongylus and Paragonimus that can be administered in Kittens, Puppies and Cats.

Pharmacodynamic properties:

Fenbendazole is an anthelmintic belonging to the benzimidazole carbamates group. It acts by interfering in the energy metabolism of the nematode. The anthelmintic efficacy is based on the inhibition of the polymerisation of tubulin to microtubuli. The anthelmintic affects both adult and immature stages of gastrointestinal and respiratory nematodes.

Pharmacokinetic particulars:

Fenbendazole is only partly absorbed after oral administration and is then metabolised in the liver. Fenbendazole and its metabolites are distributed throughout the body and high concentrations can be found in the liver. The elimination of fenbendazole and its metabolites occurs primarily via the faeces (>90%) and to a small extent in the urine and milk.

Fenbendazole is metabolised to its sulphoxide, then to sulphone and amines.

Chemical Name: Methyl N-(6-phenylsulfanyl-1H-benzoimidazol-2-yl) carbamate.

Class: Dewormer

Indication / Uses:

A broad spectrum anthelmintic for the treatment of domestic cats and dogs infected with immature and mature stages of nematodes of the gastrointestinal and respiratory tracts.

Removal and control of Hookworms, Roundworms, Tapeworms and Whipworms

Adult cats and dogs:

For the treatment of adult cats and dogs infected with gastro-intestinal nematodes and cestodes:
Ascarid spp. (Toxocara canis, Toxocara cati, Toxascaris leonine)
Ancylostoma spp. Trichuris spp.
Uncinaria spp. Taenia spp.

Kittens and Puppies:

For the treatment of puppies and kittens infected with gastrointestinal nematodes and puppies infected with protozoa (Giardia spp.).

Dosage and administration:

Kittens and Puppies under 6 months of age:

0.5 ml per kg body weight daily for 3 consecutive days given by mouth directly after feeding to unweaned animals or added to feed for weaned animals, directly before feeding.

Pregnant cats:

Pregnant cats can be safely treated but only require a single treatment at the routine adult dose rate. Administer 1ml per kg body weight as a single dose.

Pregnant dogs:

1 ml per 4 kg body weight daily from day 40 of pregnancy continuously to 2 days post-whelping (approximately 25 days) (=25 mg Fenbendazole/kg body weight daily)

Increased dosing for specific infections:

For the treatment of clinical worm infestations in adult dogs and cats or Giardia spp. infections in dogs, administer ml per 2 kg body weight daily for 3 consecutive days (= 50 mg Fenbendazole/kg body weight daily for 3 days).

For the control of lungworm Oslerus (Filaroides) osleri in dogs

Administer 1 ml per 2 kg body weight for 7 consecutive days (= 50 mg Fenbendazole/kg body weight daily for 7 days).

A repeat course of treatment may be required in some cases.